Australian Jarmila Gajdosova was the first up on Rod Laver Arena to begin the Australian Open and she struggled in the first set with German ninth-seed Angelique Kerber taking it out six games to three.
However, Gajdosova hit back ferociously in the second set racing through it without allowing the German to win a single game to have all the momentum going into the third set.
The Australian couldn’t keep her form going, though, and the more-fancied Kerber steadied to advance to the second round recoding the 6-3, 0-6, 6-2 victory with 31 unforced errors and six double-faults from Gajdosova proving costly in the finish.
Dellacqua was another Australian woman in action on the opening day and she pulled off a terrific straight-sets victory over former world No. 2 Russian Vera Zvonareva.
Zvonareva is on the comeback trail from more than a year out of the game, but it was still an outstanding performance from the West Australian to dominate the match and win 6-2, 6-2 while her opponent hit a massive 43 unforced errors.
Stosur then became the second Australian woman to win through to the second round beating Czech Klara Zakapalova 6-3, 6-4 but it was a much tougher contest than the scoreline suggests.
After the Australian 17th-seed claimed the opening set impressively, the woman who beat her at last week's Hobart International found some of that form again to race out to a 4-1 lead in the second set.
However, Stosur found a way to claw back into the contest and win the next five games on the trot to advance to the second round in the process.
The ever-popular Li Na had no trouble advancing to the season round dropping just two games in the process easily beating Croatia's Ana Konjuh on Hisense Arena.
Former world No. 1 Ana Ivanovic had a tough battle with Dutchwoman Kiki Bertens, but ended up winning in straight-sets still 6-4, 6-4 to advance through to the second round.
Venus Williams might not be seeded at this year's Australian Open, but has been the biggest name eliminated on the opening day of women's action as she stumbled on her comeback trail from injury.
Williams looked outstanding in the first set racing through it 6-2 and then early in the second, but Russia's 22nd-seed Ekaterina Makarova steadied and ended up winning the match 2-6, 6-4, 6-4 on Margaret Court Arena.
Heather Watson then became the first of two British women casualties on the opening day with Slovak veteran and 31st-seed Daniela Hantuchova beating her in three sets, 7-5, 3-6, 6-3.
Laura Robson then joined her on the sidelines as she continued to struggle with a wrist injury as 18th-seeded Belgian Kirsten Flipkens cruised to a 6-3, 6-0 victory.
American Irina Falconi continued Spanish veteran Anabel Medina Garrigues' miserable time in Australia this summer that started at the Hopman Cup, winning 6-3, 6-1 in Court 5.
Portugal's Monica Puig won through to the second round with a comfortable 6-2, 6-4 win over Georgia's Anna Tatishvili.
Veteran Frenchwoman Virginie Razzano had a tough battle against Belgian Alison van Uytvanck with both sets going to a tie-break, but she prevailed in each to end up winning 7-6, 7-6.
Japanese veteran Kimiko Date-Krumm is also out of the Australian Open in the first round with Swiss Belinda Bencic beating her in three sets, 6-4, 4-6, 6-3.
Russian Alla Kudryavtseva is also through to the second round having beaten Frenchwoman Caroline Garcia 6-2, 7-6 out on Court 19.
Emerging Canadian star and 30th-seed Eugenie Bouchard scored a solid win also over China's Hao Chen Tang, winning 7-5, 6-1.
German Annika Beck didn’t drop a game on her way to a thumping 6-0, 6-0 win over Croatia's Petra Martic on Court 13.
Italian veteran Flavia Pennetta finished 2013 in tremendous form making the semi finals of the US Open and she's now cruised into the second round of the first Grand Slam since with a thumping 6-0, 6-1 over Romania's Alexandra Cadantu.
American Madison Keys came through in the toughest women's battle of the Australian Open so far winning nine games to seven in the third set as she won through to the second round eventually beating Austria's Patricia Mayr-Achleitner 6-2, 6-7, 9-7.
Czech Lucie Hradecka had another convincing win beating Donna Vekic 6-3, 6-1 on Court 10.
Another player from the Czech Republic, Karolina Pliskova dropped just one game on her way to a crushing victory over Frenchwoman Pauline Parmentier 6-0, 6-1.
Italian Sara Errani became the first high-seed casualty in the Australian Open when the world No. 7 was ousted by German Julia Goerges, who prevailed 6-3, 6-2 on Margaret Court Arena.
German Mona Barthel is into the second round beating Chinese veteran Saisai Zheng 7-6, 6-3 on Court 8.
Romania's Monica Niculescu was another Australian Open Round 1 winner downing Israel's Shahar Peer 6-4, 6-1.
There was another three-set battle out on Court 10 with Serbia's Vesna Dolonc eventually prevailing 2-6, 6-2, 6-4 over Spain's Lara Arruabarrena.
Czech No. 26 seed Lucie Safarova also needed three sets but managed to beat Israel's Julia Glushko to get through to the second round.
Czech world No. 6 and former Wimbledon champion Petra Kvitova then provided the shock of the opening day when she was bundled out by little known Luksika Kumkhum from Thailand, who stunned the hard-hitting left-hander winning 6-2, 1-6, 6-4 on Margaret Court Arena.
Belgian Yanina Wickmayer is also through to the second after beating German Dina Pfizenmaier 7-6, 6-3 on Court 10.
There was yet another upset with another women's seed falling with young American Alison Riske upsetting Russian 23rd-seed Elena Vesnina.
The American 23-year-old cruised into the second round with the emphatic 6-2, 6-2 victory over her more fancied opponent.
Sydney International winner Tsvetana Pironkova continued on her good form in Australia with a first round straight-sets victory over Spaniard Silvia Soler-Espinosa with the Bulgarian prevailing 6-3, 6-2.
Lauren Davis then prevailed in a battle of Americans on Court 2 with her winning 6-3, 6-3 over Sachia Vickery.