Playing in hot and humid conditions which forced the activation of the NRL's heat rule, the Titans were relentless against a woeful Raiders outfit, running in six unanswered tries as temperatures soared past 30 degrees.
The victory margin is the biggest in the Titans' history, eclipsing their 38-12 win over Parramatta in 2007, while their 30-0 halftime advantage was also a new high for the club.
Matt Srama and Albert Kelly both scored first-half doubles for the Titans, with Kelly's second coming after a length-of-the-field break by Jamal Idris sent the former Cronulla playmaker into the clear.
The Raiders, who have endured a miserable week including the sacking of star fullback Josh Dugan, head back to the nation's capital winless from their opening two fixtures of the season.
The visitors were simply never in Sunday's game, racking up 35 missed tackles and completing just 22 of their 37 sets.
They will also have a nervous wait after forward Tom Learoyd-Lahrs was placed on report in the 72nd minute for a shoulder charge on Titan Ryan James.
The Titans host Manly next weekend while the Raiders welcome St George Illawarra to Canberra.