Starc was a victim of Australia's controversial rotation policy when he was rested for the Boxing Day Test against Sri Lanka.
But such is his irresistible form - five wicket hauls in successive games - Clarke admitted it would be impossible to leave the in-form left-armer out of his team.
As long as he has adequately recovered from the Perth double header and the long flight from the west coast.
Australia has the series win in their sights at Canberra's Manuka Oval after going 2-nil up in the five-match series.
And the pain is set to continue for the West Indies, with Clarke announcing he hopes to give Starc more time with the ball.
"I need to speak to the coach (Mickey Arthur) when he gets back from training to see how all the boys pull up," Clarke told reporters in Canberra on Tuesday.
"But if Mitchell's fit, he'll be playing, yes."
Shane Watson is expected to make his long-awaited return from a calf injury under Manuka Oval's newly installed floodlights.
Clarke said while he ranked Watson as one of Australia's top six batsmen in all three forms of the game, he would like to see him continue as an all-rounder.
"I think everybody including Shane is hoping that if he comes back and gets into his batting and he's scoring runs and is a part of the Australian team, he can slowly get back into his bowling as well," Clarke said.
According to Clarke Australia's success in the series could be put down to keeping West Indies guns Chris Gayle and Kieron Pollard quiet.
"That is going to be important again tomorrow for us to have success," he said.
"But we know if the likes of Gayle and Pollard get in, they're very hard to stop."
The West Indies will go into the match with somewhat of a home ground advantage.
It will be the Australian team's first-ever match on the ground, whereas the West Indies played the Prime Minister's XI there a week ago when more than 640 runs were scored.
Clarke said he'd had a look at the pitch and called up his friend and former Canberra Comets wicket keeper Brad Haddin for some advice.
"It probably suits batting," Clarke said.
"You don't have to worry about as much pace and bounce in the wicket.
"It allows you to play a lot freer at the start of your innings, you can afford to take more risks at the start of your innings."
Australian squad: Michael Clarke (c), George Bailey, Ben Cutting, Xavier Doherty, James Faulkner, Aaron Finch, Phillip Hughes, Mitchell Johnson, Glenn Maxwell, Clint McKay, Mitchell Starc, Matthew Wade, Shane Watson.